BES Genomic sequences BES Phylogeny file BES Phylogeny file with bootstrap

Minimum number of tobacco BES genes: 19

Count of tobacco BES sequences: 23

Pfam accession: DUF822

SHOULD possess DUF822 domain

This group of proteins contains members of the BZR1/LAT61 family of plant transcriptional repressors involved in controlling the response to Brassinosteroids (BRs). BRs are plant hormones that play essential roles in growth and development. BZR1 binds directly to DNA repressing the synthesis of genes involved in BR synthesis. Phosphorylation of BZR1 by BIN1 targets BZR1 to the 20S proteosome, while dephosphorylation leads to nuclear accumulation of BZR1.

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Papers

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J. A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Cell. 2005 Jan 28;120(2):249-59. PMID: 15680330



Number of contigs: 19

Number of singlets: 4

Number of N terminal – 17

Number of C terminal – 4

Number of full – 2

Total minimum number – 19




Search sequences and info


Transcription factor sequences
Locus
Description
NCBI
BES_1 [comment=C terminal] ET049718
ET051812
BES_2 [comment=N terminal] ET043505
ET043555
BES_3 [comment=N terminal] ET049365
ET049614
BES_4 [comment=N terminal] ET049332
ET048865
ET046139
BES_5 [comment=N teminal] ET050125
ET045952
ET048969
BES_6 [comment=N terminal] ET048509
ET048012
ET050090
BES_7 [comment=N terminal] ET046784
ET051301
ET046785
BES_8 [comment=C terminal] ET049333
ET048422
ET042827
ET043326
BES_9 [comment=N terminal] ET048975
ET041701
ET049833
ET041734
BES_10 [comment=N terminal] ET045865
ET041989
ET045866
ET042967
BES_11 [comment=N terminal] ET050473
ET048308
ET046760
ET043772
BES_12 [comment=N terminal] ET047675
ET047673
ET048962
ET047413
BES_13 [comment=full] ET048925
ET048924
ET042055
ET042054
ET050749
BES_14 [comment=N terminal] ET047085
ET044868
ET050814
ET047084
ET049717
BES_15 [comment=N terminal] ET051805
ET045508
ET050971
ET044839
ET045509
BES_16 [comment=N terminal] ET042849
ET043792
ET046024
ET045635
ET042850
ET042173
BES_17 [comment=N terminal] ET043481
ET051753
ET044774
ET045529
ET051239
ET051877
BES_18 [comment=N terminal] ET042123
ET049336
ET048450
ET043680
ET043973
ET042124
ET049051
ET045593
BES_19 [comment=C terminal] ET046474
ET045448
ET042748
ET042747
ET051255
ET041991
ET041990
ET043378
ET044140
ET044094
ET051256
ET050187
BES_20 [comment=N terminal] ET045786
BES_21 [comment=full] ET047262
BES_22 [comment=C terminal] ET043752
BES_23 [comment=N terminal] ET045777


Tobacco published genes related to transcription factor family BES
Family Genbank ID Name
Authors of this site:

Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko

Contact:

pr8y@virginia.edu