C2H2 Genomic sequences

Minimum number of tobacco C2H2 genes: 161

Count of tobacco C2H2 sequences: 199

Pfam accession: C2H2

SHOULD possess zf-C2H2 domain but SHOULD NOT possess JmjC JmjN PHD domains

The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.

C2H2 zinc fingers (ZF) display a wide range of functions, from DNA or RNA binding to the involvement in protein-protein interactions. Therefore ZFPs not only act in transcriptional regulation, either directly or through site-specific modification and/or regulation of chromatin, but also participate in RNA metabolism and in other cellular functions that probably require specific protein contacts of the ZF domain.

Through in silico analysis 176 zinc finger proteins in Arabidopsis thaliana that hence constitute the most abundant family of putative transcriptional regulators in this plant were found. Only a minority of 33 A. thaliana zinc finger proteins are conserved in other eukaryotes. In contrast, the majority of these proteins (81%) are plant specific. They are derived from extensive duplication events and form expanded families. We assigned the proteins to different subgroups and families and focused specifically on the two largest and evolutionarily youngest families (A1 and C1) that are suggested to be primarily involved in transcriptional regulation. The newly defined family A1 (24 members) comprises proteins with tandemly arranged zinc finger domains. Family C1 (64 members), earlier described as the EPF-family in Petunia, comprises proteins with one isolated or two to five dispersed fingers and a mostly invariant QALGGH motif in the zinc finger helices. Based on the amino acid pattern in these helices we could describe five different signature sequences prevalent in C1 zinc finger domains. We also found a number of non-finger domains that are conserved in these families.

Analysis of the few evolutionarily conserved zinc finger proteins of A. thaliana suggests that most of them could be involved in ancient biological processes like RNA metabolism and chromatin-remodeling. In contrast, the majority of the unique A. thaliana zinc finger proteins are known or suggested to be involved in transcriptional regulation. They exhibit remarkable differences in the features of their zinc finger sequences and zinc finger arrangements compared to animal zinc finger proteins. The different zinc finger helix signatures found in family C1 may have important implications for the sequence specific DNA recognition and allow inferences about the evolution of the members in this family.

Papers

Iuchi, S. Three classes of C2H2 zinc finger proteins. Cell. Mol. Life Sci. 2001. 58(4):625-35 PMID: 11361095

Takatsuji, H. Zinc-finger proteins: the classical zinc finger emerges in contemporary plant science. Plant Mol. Biol. 1999 39(6):1073-8 PMID: 10380795

Englbrecht, CC; Schoof, H; Böhm, S. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. BMC Genomics 2004. 5(1):39 PMID: 15236668

Sakamoto, H; Maruyama, K; Sakuma, Y; Meshi, T; Iwabuchi, M; Shinozaki, K; Yamaguchi-Shinozaki, K. Arabidopsis Cys2/His2-type zinc-finger proteins function as transcription repressors under drought, cold, and high-salinity stress conditions. Plant Physiol. 2004. 136(1):2734-46 PMID: 15333755



Number of contigs: 149

Number of singlets: 50

Minimum numbner 40 + 34 + 18 + 37 + 1 + 1 + 2 + 3 + 1 + 1 +23* = 161 minimum

Searched with:

A1a At1g03840 (whole protein)

A1b At1g68130 (whole protein)

A1c AT1g34370 (whole protein)

A1d At1g51220 (whole protein)

A3 At2g23740 (region spanning the 4 fingers)

A4 at1g30970 (two fingers)

B1 at1g72050 (whole protein)

C1-1i At1g640 (single finger)

C1-Sa AT2G15740 (single finger)

C1-Q At2g36475 (single finger)

C1-2i AT2G37430 (two fingers)

C1-3i AT1G02030 (whole finger)

C1-4i AT1G49900 (two searches with the two double finger regions)

C1-5i AT3G29340 (whole protein - six fingers)

C2-B AT1G65110 (single finger)

C2-sb AT4G26030 (single finger)

C2-pairs AT4G12240 (single finger)

C2-unique AT1G04445 (single finger)

C2-cons SF AT2G27100 (single finger)

C3-PL SF AT1G01350 (single finger)

Results:

A1 23 + 3 + 1 + 2 = 40 minimum

N-terminal half 34

C-terminal half 11

Second finger 3

Central part 1

Full 2

C1-2i 32 + 2 = 34 minimum

Full 32

First finger 2

Second finger 1

C1-3i 13 + 4 + 1 = 18 minimum

Full 13

1 + 2 fingers 4

2 + 3 fingers 1

First finger 1

C1-1i = 37 minimum

Full 37

C2 cons = 1 minimum

Full 1

C2 pairs = 1 minimum

Full = 1

B cons 1 + 1 = 2 minimum

Full 1

C-terminal 1

N-terminal 1

C-4i 2 + 1 = 3 minimum

Full 2

First three fingers 1

C1-Q = 1 minimum

Full 1

A4 cons = 1 minimum

First finger 1

Multiple C2H2 fingers but no hits to plant proteins: 23

As we have no basis for comparison, then all 23 are included.




Search sequences and info


Transcription factor sequences
Locus
Description
NCBI
C2H2_1 [comment=similar to WIP2 (At3g57670). Is part of an A1 pl-sf. Contains only one finger of probably four. First half of C-terminal part.] ET047140
C2H2_2 [comment=99% identical to Nicotiana tabacum osmotic stress-induced zinc-finger protein (zfp)(AF053077). Contains the first of two QALGGH zinc fingers. (C1-2i)] ET045329
C2H2_3 [comment=Full most similar to ZFP5 (C1-1i) and has the single finger (RALGGH).] ET051660
C2H2_4 [comment=Full as contains parts of both fingers most similar to Zat12 (C1-2i)] ET051836
C2H2_5 [comment=Full as contains both fingers. Most similar to ZAT11 (C1-2i)] ET051456
C2H2_6 [comment=full most similar to At3g53820 (C1-1i). Contains the single zinc finger.] ET051552
C2H2_7 [comment=most similar to ATIDD2 (AT3G50700) (A1). Contains first half of first finger out of four.] ET045335
ET050442
C2H2_8 [comment=full most similar to AT5G14010.1 (C1-1i). Contains single finger.] ET049979
ET043257
C2H2_10 [comment=Full contains both zinc fingers. Most similar to At2g28710 (C1-2i)] ET048562
ET049800
C2H2_11 [comment=Full. Most similar to At4g17810 (C1-1i) and has the single finger.] ET048838
ET045402
C2H2_13 [comment=Most similar to WIP2 (At3g57670) (A1). First half containing the first finger.] ET042601
ET044808
C2H2_16 [comment=Full. Most similar to At2g28710 (C2 cons). Contains the single finger.] ET043261
ET043260
C2H2_17 [comment=Full contains both zinc fingers. Similar to AT2G26940 (C1-2i)] ET050135
ET051397
C2H2_18 [comment=Full. Contains both zinc fingers. Very similar to PIF1 [Nicotiana benthamiana] (AAQ54303). Similar to ZAT10 (C1-2i).] ET041953
ET041954
C2H2_19 [comment=Full. Contains the single finger. Similar to ZFP4 (At1g66140) (C1-1i)] ET046357
ET042098
C2H2_20 [comment=Full. Similar to At2g28710 (C1-2i) and contains both fingers.] ET049178
ET051170
C2H2_22 [comment=Full. Similar to ZAT11 (C1-2i). Contains both fingers.] ET051158
ET051157
C2H2_24 [comment=Full. Similar to At1g68360. Contains the single finger. (C1-1i).] ET050829
ET049559
C2H2_25 [comment=Similar to AT4G35280 (C1-3i). Has first two of three fingers.] ET044764
ET049243
C2H2_26 [comment=Full. Similar to ZAT5 (AT2G28200) (C1-2i) contains both fingers] ET045239
ET048503
C2H2_27 [comment=Similar to At2g28710 (C1-2i) and contains both fingers.] ET048645
ET048644
C2H2_28 [comment=Similar to At1g02040 (C1-2i). Contains the first of two fingers.] ET050387
ET050203
C2H2_29 [comment=Full. Similar to At2g28710 (C1-2i) Contains both fingers.] ET044415
ET048813
C2H2_30 [comment=Very similar to At2g02080 (A1) Has at least the first two fingers (of four?) May only have two.] ET044235
ET048348
C2H2_31 [comment=Similar to At1g26590 (C1-3i). Contains first two fingers (of three).] ET042455
ET046022
C2H2_33 [comment=Similar to At2g02070 (A1). Appears to be an INDETERMINATE-related protein and contain the first two of four(?) fingers.] ET049551
ET048404
C2H2_34 [comment=Full. Similar to At2g28710 (C1-2i). Has both fingers.] ET047854
ET047926
C2H2_35 [comment=Full. Most similar to ZAT11 (At2g37430) (C1-2i) and has both fingers. ] ET049117
ET048206
C2H2_36 [comment=Seems to contain many zinc fingers but is unusual as all hits were to animal proteins.] ET044731
ET044732
C2H2_37 [comment=Full. Similar to AT5G03510 (C1-2i). Has both fingers.] ET042004
ET050414
C2H2_38 [comment=Similar to AT5G66730 (Ai). Has first two fingers of possibly four.] ET045442
ET047432
C2H2_39 [comment=Similar to At3g50700 (A1) INDETERMINATE(ID)-DOMAIN 2. Has the first two fingers of four.] ET047201
ET051457
C2H2_41 [comment=Full. Similar to JAGGED (Ay6g68480) (C1-1i). Contains the single finger.] ET049348
ET049357
C2H2_42 [comment=Full. Similar to ZFP5 (At1g10480) (C1-1i). Contains the single finger.] ET044523
ET044522
C2H2_43 [comment=Similar to INDETERMINATE(ID)-DOMAIN 14 (At1g68130) (A1). Appears to contain the first two domains of four(?)] ET042044
ET043325
C2H2_44 [comment=Full. Similar to ZFP6 (At1g67030) (C1-1i). Contains the single finger.] ET045962
ET050939
C2H2_45 [comment=Full. Similar to Superman (At3g23130) (C1-1i). Contains the single finger.] ET047913
ET044802
C2H2_46 [comment=Similar to At3g50700 (A1) INDETERMINATE(ID)-DOMAIN 2. Has the second of four (two?) fingers.] ET042768
ET048831
C2H2_47 [comment=Full. Similar to At1g68130 (A1) INDETERMINATE(ID)-DOMAIN 14. Has the two (more?) fingers.] ET045053
ET049181
ET045052
C2H2_48 [comment=Full. Similar to (AT2G37740) (C1-1i) ZFP10 and RABBITEARS. Contains the single finger.] ET048840
ET051801
ET045130
C2H2_49 [comment=A1 protein part of second zinc finger. ] ET050400
ET048282
ET050046
C2H2_50 [comment=Similar to WIP3 (A1) At1g08290. Contains parts of 2-3 fingers and is almost full length wrt them. C-terminal half.] ET051062
ET043390
ET051061
C2H2_51 [comment=Full. Similar to ZAT11 (AT2G37430) (C1-2i). Has both domains.] ET042800
ET051894
ET043290
C2H2_52 [comment=Full. Similar to ZFP5 (C1-1i) (At1g10480). Contains the single finger.] ET044006
ET048613
ET042835
C2H2_53 [comment=Full. Similar to ZFP1 (At1g80730) (C1-1i). Contains the finger.] ET045852
ET051711
ET050314
C2H2_55 [comment=Full. Similar to AT4G17810 (C1-1i). Contains the single finger.] ET049422
ET051284
ET047439
C2H2_56 [comment=Similar to INDETERMINATE(ID)-DOMAIN 4 (AT2G02080) (A1). Contains first two domains of four.] ET049873
ET043099
ET043629
C2H2_57 [comment=Similar to AT1G14580 (A1). Contains first two domains of four.] ET050071
ET048651
ET048650
C2H2_58 [comment=Similar to AT1G34370 (A1). Contains the C-terminal half and at least 2 fingers.] ET050737
ET042324
ET047431
C2H2_59 [comment=Full. Similar to ZAT11 AT2G37430 (C1-2i). Contains both fingers.] ET045344
ET045345
ET047089
C2H2_60 [comment=Full. Similar to ZAT11 AT2G37430 (C1-2i). Contains both fingers.] ET046736
ET043119
ET048710
C2H2_61 [comment=Similar to WIP3 (AT1G08290) (A1) C-terminal half and most of the fingers.] ET050666
ET047141
ET043906
C2H2_62 [comment=Similar to (AT5G03150) (A1). Contains first two fingers.] ET048864
ET045286
ET051547
C2H2_63 [comment=Full. Has similarity (but low) to ZFP7 (At1g24630) (C1-1i). Contains the single finger.] ET042962
ET050640
ET050589
C2H2_64 [comment=Similar to INDETERMINATE(ID)-DOMAIN 14 (AT1G68130) (A1). Contains the first half and first 2 fingers.] ET051816
ET049286
ET042638
C2H2_65 [comment=Similar to At1g03840 (A1). Contains the first half and first 2 fingers.] ET049145
ET042190
ET049030
C2H2_66 [comment=Similar to WIP6 (At1g13290). Contains the first half and first 2 fingers.] ET045159
ET045158
ET045160
C2H2_67 [comment=Similar to ID1-like protein 3 (At5g03150) (A1). Contains the first half and first 2 fingers.] ET046113
ET049335
ET042777
C2H2_68 [comment=Full. Similar to ZAT5 (At2g28200) (C1-2i). Contains both fingers.] ET042808
ET042807
ET045872
C2H2_69 [comment=Similar to At1g03840 (A1). Contains the first half and first 2 fingers.] ET044565
ET044566
ET051488
C2H2_70 [comment=Similar to AT4G35280 (C1-3i). Contains first two (of three) fingers.] ET051164
ET044818
ET042761
C2H2_71 [comment=Full. Similar to AT4G16610 (C1-1i). Contains the single finger.] ET043632
ET045369
ET045850
C2H2_72 [comment=Full. Similar to ZAT11(At2g37430) (C1-2i). Contains both fingers.] ET043468
ET047615
ET047614
C2H2_73 [comment=Full. Similar to ZFP4 (At1g66140) (C1-1i). Contains finger. ] ET046120
ET046119
ET043273
C2H2_75 [comment=Similar to INDETERMINATE(ID)-DOMAIN 4 (AT2G02080) (A1). Contains the first half and first 2 fingers.] ET049168
ET047724
ET049783
C2H2_76 [comment=Full. Similar to At5g52010 (C2 pairs). Contains single finger.] ET048787
ET047524
ET047582
C2H2_78 [comment=Full. Similar to SUPERMAN (At3g23130) (C1-1i). Contains the single domain.] ET047557
ET043177
ET049013
C2H2_79 [comment=Full. Very similar but not identical to osmotic stress-induced zinc-finger protein [Nicotiana tabacum] (AAC06243). Similar to ZAT10 (At1g27730) (C1-2i). Contains both zinc fingers.] ET046909
ET051489
ET051277
C2H2_81 [comment=Full. Similar to ZFP5 (At1g10480) (C1-1i). Has the only finger.] ET050192
ET048167
ET049389
C2H2_82 [comment=Full. Similar to AT2G26940 (C1-2i). Has both fingers.] ET045468
ET044175
ET050386
C2H2_83 [comment=Similar to TT1 (At1g34790) (A1). Contains the C-terminal half and several fingers.] ET049081
ET043842
ET050051
C2H2_84 [comment=Similar to WIP3 (At1g08290) (A1). Contains N-terminal half and several fingers.] ET042245
ET050202
ET043385
C2H2_85 [comment=Full. Similar to SUPERMAN (At3g23130) (C1-1i). Contains the single domain.] ET043527
ET047848
ET045196
C2H2_86 [comment=Full. Similar to ZAT1 (AT1G02030) (C1-3i). Contains all three fingers.] ET042268
ET042251
ET045588
C2H2_87 [comment=Full. Similar to (AT1G26610) (C1-3i). Contains all three fingers.] ET050085
ET050086
ET044765
C2H2_88 [comment=Full. Similar to ZFP2 (At5g57520) (C1-1i). Contains single finger.] ET043395
ET045973
ET044950
C2H2_89 [comment=Similar to ID1-like protein 3 (AT5G03150) (A1). Contains N-terminal half and several fingers.] ET049936
ET047975
ET046421
ET043296
C2H2_90 [comment=Full. Similar to AT3G53820 (C1-1i). Contains single finger.] ET050913
ET047842
ET050184
ET051548
C2H2_91 [comment=Similar to ID1-like protein 3 (AT5G03150) (A1). N-terminal end. Has several fingers.] ET045424
ET048981
ET048980
ET049555
C2H2_92 [comment=Full. Similar to ZAT11 (AT2G37430) (C1-2i). Has both fingers.] ET041754
ET041753
ET047515
ET047514
C2H2_93 [comment=Full. Similar to (AT1G26610) (C1-3i). Contains all three fingers.] ET049232
ET046575
ET049233
ET047093
C2H2_94 [comment=Similar to AT3g13810/MCP4_2 (A1). Contains the N-terminal half and several fingers.] ET042527
ET045226
ET047297
ET051424
C2H2_95 [comment=Full. Similar to ZFP5 (At1g10480) (C1-1i). Has the single finger.] ET044518
ET047746
ET046260
ET047747
C2H2_96 [comment=Similar to WIP2 (At3g57670) (A1). C-terminal end and contains several fingers.] ET042390
ET050740
ET042391
ET044908
C2H2_97 [comment=Similar to INDETERMINATE(ID)-DOMAIN 4 (AT2G02080) (A1). Contains the N-terminal end and one finger.] ET043004
ET042681
ET049045
ET043317
C2H2_98 [comment=Full. Similar to ZFP8 (At2g41940) (C1-1i). Contains the single finger.] ET047500
ET046199
ET043250
ET048579
C2H2_100 [comment=Similar to At3g57670 (WIP2) (A1). C-terminal half. Contains several fingers.] ET050185
ET043393
ET045410
ET048077
C2H2_102 [comment=Full. Similar to At1g68360 (C1-1i). Has the single finger.] ET049215
ET044882
ET050888
ET041689
C2H2_103 [comment=Full. Similar to Knuckles (At5g14010) (C1-1i). Has the single finger.] ET050676
ET051577
ET041814
ET041813
C2H2_104 [comment=Full. Similar to ZFP7 (AT1G24625) (C1-1i). Contains the single finger.] ET045758
ET047586
ET050787
ET050183
C2H2_105 [comment=Similar to AT5g44160/MLN1_8 (A1). Contains N-terminal half and several fingers.] ET045272
ET050118
ET050650
ET045273
C2H2_106 [comment=Full. Similar to At1g02040 (C1-2i). Contains both fingers.] ET042395
ET051859
ET049663
ET051720
C2H2_107 [comment=Full. Similar to TFIIIA (At1g72050). (B cons). Missing last 55 amino acids but appears to contain all fingers.] ET044470
ET051700
ET044750
ET044751
C2H2_108 [comment=Full. Similar to Superman (At3g23130) (C1-1i). Contains the single finger.] ET048292
ET051347
ET047914
ET049476
C2H2_109 [comment=Full. Similar to ZFP4 (At1g66140) (C1-1i). Contains the single finger.] ET047996
ET045211
ET050967
ET047997
C2H2_110 [comment=Similar to AT1G68130 (A1). N-terminal half. Contains several fingers.] ET044589
ET050500
ET044590
ET043580
C2H2_111 [comment=Similar to WIP2 (At3g57670) (A1). C-terminal half and several fingers.] ET044394
ET047563
ET044395
ET047565
C2H2_112 [comment=Full. Similar to ZFP6 (At1g67030) (C1-1i). Contains the single finger.] ET048257
ET045981
ET050910
ET042994
C2H2_113 [comment=Full. Similar to (AT1G26610) (C1-3i). Contains all fingers.] ET046851
ET044876
ET048269
ET044875
C2H2_114 [comment=Similar to AT1G03840 (A1). N-terminal half contains several fingers.] ET046844
ET047857
ET049206
ET046845
C2H2_115 [comment=Similar to AT1G26610 (C1-3i). Has first two fingers (of three).] ET043928
ET047791
ET047311
ET046689
C2H2_116 [comment=Similar to AT3G50700 (A1). Contains N-terminal half and several fingers.] ET042270
ET047923
ET042269
ET042569
C2H2_117 [comment=Full. Similar to ZFP7 (At1g24630 (C1-1i). Contains the single finger.] ET044307
ET046372
ET046476
ET044306
C2H2_118 [comment=Full. Similar to ZFP1 (At1g80730) (C1-1i). Contains the single finger.] ET049079
ET043594
ET048190
ET042200
C2H2_119 [comment=Similar to AT1G34370 (A1). Contains C-terminal half and several fingers.] ET049735
ET041983
ET043729
ET050657
ET043676
C2H2_120 [comment=Full. Similar to AT1G26610 (C1-3i). Contains all fingers.] ET046978
ET042205
ET044975
ET042204
ET044976
C2H2_121 [comment=Full. Similar to AT1G02030 (ZAT1). (C1-3i). Contains all fingers.] ET046852
ET045040
ET047312
ET044680
ET042456
C2H2_122 [comment=Full. Similar to AT2G28200 (ZAT5) (C1-2i). Contains both fingers.] ET047309
ET043484
ET050890
ET048118
ET051137
C2H2_123 [comment=Full. Similar to ZFP1 (At1g80730) (C1-1i). Contains the single finger] ET044667
ET046598
ET043463
ET043060
ET047598
C2H2_124 [comment=Similar to AT3G45260 (A1). N-terminal half and several fingers.] ET045100
ET045101
ET046644
ET050819
ET048362
C2H2_125 [comment=Full. Similar to osmotic stress-induced zinc-finger protein [Nicotiana tabacum](AAC06243) and ZAT10 (At1g27730) (C1-2i). Has both fingers.] ET042195
ET048661
ET043884
ET043327
ET043677
C2H2_126 [comment=Full. Similar to AT3G60580 (C1-3i). Contains the three fingers.] ET048496
ET042178
ET042489
ET048495
ET042179
ET041904
C2H2_127 [comment=Full. Similar to AT3G60580 (C1-3i). Contains the three fingers.] ET051454
ET047133
ET046967
ET048058
ET046966
ET051453
C2H2_128 [comment=Full. Similar to AT2G28710 (C1-2i). Contains both fingers.] ET042781
ET046401
ET049505
ET043598
ET047150
ET042969
C2H2_129 [comment=Full. Similar to ZAT11 (At2g37430) (C1-2i). Contains both fingers.] ET051211
ET048977
ET045039
ET043071
ET049953
ET050406
C2H2_130 [comment=Similar to AT5G66730 (A1). N-terminal end and several fingers.] ET051521
ET050028
ET049895
ET044632
ET046607
ET043682
C2H2_131 [comment=Similar to AT1G68130 (A1). N-terminal half. Several fingers.] ET047339
ET048026
ET045573
ET050646
ET045294
ET047247
C2H2_132 [comment=Similar to TT1 (At1g34790) (A1). Contains C-terminal half and several fingers.] ET047993
ET047698
ET048683
ET051785
ET048395
ET048684
C2H2_133 [comment=Similar to At3g13810 (A1). N-terminal half and several fingers.] ET042749
ET042744
ET042745
ET049830
ET048335
ET048791
C2H2_134 [comment=Full. Similar to AT5G56200 (C1-4i). Contains all fingers.] ET048468
ET047175
ET044123
ET044122
ET045451
ET048469
C2H2_135 [comment=Similar to AT1G34370 (A1) N-terminal two thirds. Several fingers.] ET048119
ET042167
ET047475
ET043098
ET047075
ET042166
C2H2_136 [comment=Full. Similar to AT1G26610. (C1-3i). Contains three fingers.] ET045954
ET045029
ET049283
ET042523
ET043244
ET045028
ET043243
C2H2_137 [comment=Full. Similar to AT4G17810. (C1-1i). One finger.] ET043981
ET043840
ET050241
ET045886
ET046960
ET048353
ET045789
C2H2_138 [comment=Full. Similar to ZFP8 (At2g41940) (C1-1i). One finger.] ET049646
ET042640
ET050765
ET042641
ET042966
ET049651
ET046747
C2H2_139 [comment=Full. Similar to AT5G04390 (C1-2i). Contains both domains.] ET047631
ET046595
ET044652
ET043914
ET045684
ET048113
ET046351
C2H2_140 [comment=Full. Similar to Cys2-His2 type zinc finger protein [Nicotiana tabacum] (BAE17114) and STZ/ZAT10 (AT1G27730) (C1-2i). Contains both fingers. ] ET042285
ET042286
ET042659
ET049360
ET041697
ET048762
ET042658
ET049361
C2H2_141 [comment=Full. Similar to AT1G26610 (C1-3i). Three fingers.] ET046567
ET048874
ET048875
ET050421
ET050450
ET045589
ET050807
ET050810
C2H2_142 [comment=Full. Similar to AT1G26590 (C1-3i). Contains three fingers.] ET046556
ET043437
ET042552
ET042550
ET042549
ET042551
ET042548
ET048812
C2H2_143 [comment=Full. Similar to osmotic stress-induced zinc-finger protein [Nicotiana tabacum] (AAC06243) and STZ/ZAT10 (C1-2i). Three fingers.] ET049101
ET043946
ET050688
ET050687
ET048797
ET048798
ET051293
ET042287
C2H2_144 [comment=Full. Similar to AT5G56200 (C1-4i). All four fingers.] ET048543
ET043562
ET049074
ET048542
ET044459
ET049129
ET043563
ET048132
C2H2_145 [comment=Similar to AT1G68130 (A1). N-terminal half. Several fingers.] ET041975
ET043217
ET049294
ET041976
ET050809
ET045139
ET050265
ET046549
ET042360
C2H2_146 [comment=Full. Similar to AT2G45120 (C1-3i). All three fingers.] ET049633
ET051230
ET051231
ET048914
ET046472
ET050766
ET049300
ET043970
ET045851
C2H2_147 [comment=Full. Similar to AT1G34370 (A1). Missing parts at N- and C-terminus but appears to contain all fingers.] ET049312
ET050325
ET050052
ET048417
ET046001
ET041803
ET049311
ET041804
ET050053
ET048418
ET048568
C2H2_148 [comment=Full. Similar to At3g60580 (C1-3i). Has all three fingers.] ET045371
ET050746
ET042499
ET048956
ET051002
ET051001
ET045370
ET043073
ET043072
ET042479
ET042498
ET042851
C2H2_149 [comment=Full. Similar to AT1G02040 (C1-2i). Has all fingers.] ET048859
ET042536
ET042537
ET042540
ET042539
ET049885
ET046703
ET047974
ET049886
ET046704
ET042538
ET046482
ET048860
C2H2_150 [comment=Has at least five C2H2 fingers but does not hit a plant protein.] ET049147
C2H2_151 [comment=Full. Similar to ZFP1 (At1g80730) (C1-1i). Contains the single finger.] ET048669
C2H2_152 [comment=Has at least four C2H2 fingers but does not hit a plant protein.] ET041709
C2H2_153 [comment=Similar to AT1G72050 (TFIIIA) (B cons). Only has the last C-terminal 80 amino acids.] ET041808
C2H2_154 [comment=Similar to AT5G03150 (A1). Contains central portion and several fingers.] ET049556
C2H2_155 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET042113
C2H2_157 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET046114
C2H2_158 [comment=Kruppel-like zinc finger. Has at several C2H2 fingers but does not hit a plant protein.] ET050146
C2H2_159 [comment=Similar to AT4G35280 (C1-3i). Has second and third fingers.] ET046414
C2H2_162 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET048361
C2H2_163 [comment=Full. Similar to AT2G36475 (C1-Q). C-terminal 150 amino acids but contains the single finger.] ET045489
C2H2_164 [comment=Very similar to WREBP-2 [Nicotiana tabacum] (BAA75685). Has a predicted C2H2 zinc finger. Also similar to AT4G06634 (A4 cons). Has one finger of three.] ET043286
C2H2_165 [comment=Similar to WIP1 (A1). Has N-terminal half and first of 4 fingers.] ET048396
C2H2_166 [comment=Full. Similar to AT5G43540 (C1-1i). Has the single finger.] ET044637
C2H2_168 [comment=Similar to AT1G26610 (C1-3i). First N-terminal 50 amino acids and first finger of three.] ET042394
C2H2_169 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET043055
C2H2_170 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET046791
C2H2_171 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET050429
C2H2_173 [comment=Has at several C2H2 fingers but does not hit a plant protein.] ET048829
C2H2_174 [comment=Similar to TFIIIA. N-terminus. First 50 amino acids and first finger.] ET042350
C2H2_175 [comment=Similar to AT5G56200 (C1-4i). Contains the first three fingers of four.] ET051872
C2H2_176 [comment=Full. Similar to AT1G02040 (C1-2i). Has both fingers.] ET046690
C2H2_177 [comment=Similar to At1g55110 (A1). Contains the second finger of four.] ET047489
C2H2_178 [comment=Has seven C2H2 fingers but does not hit a plant protein.] ET047111
C2H2_179 [comment=Similar to AT5G22890 (A1). C-terminal end. Several fingers.] ET049737
C2H2_181 [comment=Has at least two C2H2 fingers but does not hit a plant protein. TFIIIa-like?] ET042530
C2H2_183 [comment=Has at least four C2H2 fingers but does not hit a plant protein. TFIIIa-like?] ET046792
C2H2_185 [comment=Has at least two C2H2 fingers but does not hit a plant protein. TFIIIa-like? Krueppel-associated (KRAB)?] ET044410
C2H2_187 [comment=Has at least two C2H2 fingers but does not hit a plant protein.] ET046674
C2H2_188 [comment=Has at least three C2H2 fingers but does not hit a plant protein.] ET045152
C2H2_189 [comment=Has at least three C2H2 fingers but does not hit a plant protein.] ET046891
C2H2_190 [comment=Has at least four C2H2 fingers but does not hit a plant protein.] ET042721
C2H2_191 [comment=Very similar to drosophila kruppel. Contains at least 5 C2H2 fingers. Does not hit any plant proteins.] ET045767
C2H2_192 [comment=Has at least four C2H2 fingers but does not hit a plant protein.] ET047316
C2H2_194 [comment=Full. Similar to AT5G04390 (C1-2i). Contains both fingers.] ET048706
C2H2_195 [comment=Similar to AT5G03510 (C1-2i). Contains the second of two fingers.] ET044073
C2H2_196 [comment=Similar to At1g55110 (A1). Contains part of third finger (of four).] ET051019
C2H2_198 [comment=Has at least six C2H2 fingers but does not hit a plant protein.] ET044416
C2H2_199 [comment=Has at least four C2H2 fingers but does not hit a plant protein.] ET047419


Tobacco published genes related to transcription factor family C2H2
Family Genbank ID Name
C2H2 AB186899 ZFT1
Authors of this site:

Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko

Contact:

pr8y@virginia.edu