TOBFAC: The database of tobacco transcription factors
Family: C3H
Minimum number of tobacco C3H genes: 69
Count of tobacco C3H sequences: 71
Pfam accession: zf-CCCH
SHOULD possess zf-CCCH domain but SHOULD NOT possess PHD SNF2_N zf-C2H2 domains
Zinc finger domains are thought to be involved in DNA-binding, and exist as different types, depending on the positions of the cysteine residues. Proteins containing zinc finger domains of the C-x8-C-x5-C-x3-H type include zinc finger proteins from eukaryotes involved in cell cycle or growth phase-related regulation, e.g. human TIS11B (butyrate response factor 1), a probable regulatory protein involved in regulating the response to growth factors. It has been shown that different CCCH zinc finger proteins interact with the 3' untranslated region of various mRNA. This type of zinc finger is very often present in two copies.
Many of the proteins are C3HC4 RING finger proteins.
PEI encodes an Arabidopsis protein containing a Cys3His zinc finger domain associated with a number of animal and fungal transcription factors. In situ hybridization results showed that PEI1 is expressed throughout the embryo from globular to late cotyledon stage.
Li, Z; Thomas, TL. PEI1, an embryo-specific zinc finger protein gene required for heart-stage embryo formation in Arabidopsis. Plant Cell 1998. 10(3):383-98 PMID: 9501112
Number of contigs: 54
Number of singlets: 19
Number of N terminal (half domain) – 8
Number of C terminal (half domain) – 2
Number of full – 61
Total minimum number – 69
| Family | Genbank ID | Name |
Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko