TOBFAC: The database of tobacco transcription factors
Family: CONSTANS
Minimum number of tobacco CONSTANS genes: 40
Count of tobacco CONSTANS sequences: 45
SHOULD possess CCT zf-B_box domains
The CO gene was originally defined by an allelic series of mutants that flower late in LD and do not respond to photoperiod . CO has subsequently been shown to encode a transcription factor that plays a central role in the photoperiod detection mechanism acting between the circadian clock and genes controlling meristem identity. Griffiths et al. (2003) have defined the CO-like gene family by the presence of two conserved domains: a Zn-finger region near the N-terminus that resembles B-box domains and a region near the C-terminus called the CCT domain (Putterill et al., 1995). Using this definition, Griffiths et al. (2003) have shown that CO is part of a 17-member gene family in Arabidopsis that consists of three broad groups. Group I genes, which include CO, have two Zn-finger B-boxes near the N- terminus . Group II genes have one B-box, and Group III genes have one B-box and a second diverged Zn-finger. Mutants that affect CO function map to both the B-box and the CCT domain.
Lagercrantz, U; Axelsson, T. Rapid evolution of the family of CONSTANS LIKE genes in plants. Mol. Biol. Evol. 2000.17(10):1499-507 PMID: 11018156
Griffiths, S; Dunford, RP; Coupland, G; Laurie, DA. The evolution of CONSTANS-like gene families in barley, rice, and Arabidopsis. Plant Physiol. 2003.131(4):1855-67 PMID: 12692345
Putterill, J; Robson, F; Lee, K; Simon, R; Coupland, G. The CONSTANS gene of Arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors. Cell 1995. 80(6):847-57 PMID: 7697715
Number of contigs: 37
Number of singlets: 8
Number of B1 domains – 8
Number of B2 domains – 5
Number of B1 and B2 domains – 32
Total minimum number – 40
| Family | Genbank ID | Name |
Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko