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TOBFAC: The database of tobacco transcription factors

Family: GRAS

Minimum number of tobacco GRAS genes: 45

Count of tobacco GRAS sequences: 45

Pfam accession: GRAS

SHOULD possess GRAS domain

Members of the GRAS gene family encode transcriptional regulators that have diverse functions in plant growth and development such as gibberellin signal transduction, root radial patterning, axillary meristem formation, phytochrome A signal transduction, and gametogenesis.

Sequence analysis of the products of the GRAS (GAI, RGA, SCR) gene family indicates that they share a variable N-terminus and a highly conserved C-terminus that contains five recognizable motifs. Proteins in the GRAS family are transcription factors that seem to be involved in development and other processes. Mutation of the SCARECROW (SCR) gene results in a radial pattern defect, loss of a ground tissue layer, in the root. The PAT1 protein is involved in phytochrome A signal transduction.

GRAS proteins contain a conserved region of about 350 amino acids that can be divided in 5 motifs, found in the following order: leucine heptad repeat I, the VHIID motif, leucine heptad repeat II, the PFYRE motif and the SAW motif. Plant specific GRAS proteins have parallels in their motif structure to the animal Signal Transducers and Activators of Transcription (STAT) family of proteins which suggests also some parallels in their functions.

Papers

Pysh, LD; Wysocka-Diller, JW; Camilleri, C; Bouchez, D; Benfey, PN. The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW-LIKE genes. Plant J. 1999 18(1):111-9 PMID: 10341448

Tian, C; Wan, P; Sun, S; Li, J; Chen, M. Genome-wide analysis of the GRAS gene family in rice and Arabidopsis. Plant Mol. Biol. 2004. 54(4):519-32 PMID: 15316287

Number of contigs :35

Number of singlets:10

Number of N terminal (half domain) – 2

Number of N terminal (two thirds) – 1

Number of C terminal (two thirds) – 1

Number of full – 41

Total minimum number – 45

Search sequences and info

Transcription factor sequences

Tobacco published genes related to transcription factor family GRAS

Authors of this site:

Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko

Contact:

pr8y@virginia.edu