TOBFAC: The database of tobacco transcription factors
Family: GRF
Minimum number of tobacco GRF genes: 23
Count of tobacco GRF sequences: 31
Pfam accession: GRF
SHOULD possess GRF domain
A novel gene GROWTH-REGULATING FACTOR1 (OsGRF1) encodes a transcription factor that appears to play a regulatory role in stem elongation. GRF proteins contain the characteristic regions- QLQ (Gln, Leu, Gln) and WRC (Trp, Arg, Cys) - as well as features indicating a function in transcriptional regulation. Most AtGRF genes are strongly expressed in actively growing and developing tissues, such as shoot tips, flower buds, and roots, but weakly in mature stem and leaf tissues. Overexpression of AtGRF1 and AtGRF2 resulted in larger leaves and cotyledons, as well as in delayed bolting of the inflorescence stem when compared to wild-type plants. In contrast, triple insertional null mutants of AtGRF1-AtGRF3 had smaller leaves and cotyledons, whereas single mutants displayed no changes in phenotype and double mutants displayed only minor ones. The alteration of leaf growth in overexpressors and triple mutants was based on an increase or decrease in cell size, respectively. This indicates that AtGRF proteins play a role in the regulation of cell expansion in leaf and cotyledon tissues.
Kim, JH; Choi, D; Kende, H. The AtGRF family of putative transcription factors is involved in leaf and cotyledon growth in Arabidopsis. Plant J. 2003. 36(1):94-104 PMID: 12974814
Number of contigs: 25
Number of singlets: 6
Number of N terminal – 18
Number of genes with middle part of the domain – 8
Number of N terminal with middle part of the domain – 5
Total minimum number – 23
| Family | Genbank ID | Name |
Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko