MYB-related Genomic sequences

Minimum number of tobacco MYB-related genes: 56

Count of tobacco MYB-related sequences: 62

Pfam accession: Myb_DNA-binding

SHOULD possess Myb_DNA-binding domain and COULD   possess zf-CCHC domain but SHOULD NOT possess ARID G2-like Response_reg SNF2_N domains

The cloning of the first transcription factor from plants, the C1 gene of maize, indicated that plants use transcription factors that are structurally related to those of animals in their control of gene expression, because C1 showed significant structural homology to the vertebrate cellular proto-oncogene c-MYB. Since 1987, the catalogue of MYB-related transcription factors has increased considerably in size due, primarily, to the ever-expanding number of MYB genes identified in higher plants (Arabidopsis thaliana is estimated to contain more than a hundred MYB genes). In vertebrates, the MYB-related proto-oncogenes comprise a small family with a central role in controlling cellular proliferation and commitment to development. However, while the functions of some plant MYB genes are relatively well understood they are, at present, quite distinct from their animal counterparts.

Papers

Jin, H; Martin, C. Multifunctionality and diversity within the plant MYB-gene family. Plant Mol. Biol. 1999. 41(5):577-85 PMID: 10645718

Klempnauer, KH; Sippel, AE. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 1987. 6(9):2719-25 PMID: 2824190

Martin, C; Paz-Ares, J. MYB transcription factors in plants. Trends Genet. 1997. 13(2):67-73 PMID: 9055608

Kirik V, Baumlein H. A novel leaf-specific myb-related protein with a single binding repeat Gene. 1996 Dec 12;183(1-2):109-13. PMID: 8996094



All have 20 amino acids in until the middle except the last two categories. Hence the total of 56 minimum.

Searched with over 10 individual MYB-related domains from Arabidopsis.

n.b Genes that contain only a single canonical R3 domain have been grouped with the R2R3MYBS. The MYB-related category here only represents divergent single domains.

We consider R2 domains with the sequence GKSCRLRW and

R3 domains with the sequence LPGRTDN not to be MYB-related.

These two are in our R2R3MYB category and are not among the MYB-related genes in DATB.

Number of contigs: 71

Number of singlets: 19

Number of N terminal – 4

Number of genes with missing less than 20 amino acids at 5’ end – 11

Number of genes with first 60% – 2

Number of genes with missing less than 20 amino acids 3’ end – 10

Number of C terminal – 4

Number of genes with first 20 amino acids – 2

Number of full – 28

Total minimum number – 56




Search sequences and info


Transcription factor sequences
Locus
Description
NCBI
MYB-related_3 [comment=one complete MYB-like domain] ET044952
ET042494
MYB-related_7 [comment=5 prime half of MYB-like domain] ET050912
ET043401
MYB-related_8 [comment=missing first 8 amino acids but otherwise complete] ET045076
ET046262
MYB-related_9 [comment=first 60%] ET042043
ET046817
MYB-related_13 [comment=missing last 8 amino acids] ET044390
ET045030
MYB-related_14 [comment=probably complete] ET050964
ET043584
MYB-related_15 [comment=full length] ET049867
ET047013
MYB-related_17 [comment=full length] ET043771
ET042610
MYB-related_19 [comment=missing last 10 amino acids very divergent] ET047043
ET047044
MYB-related_20 [comment=first two thirds. Divergent.] ET050422
ET047083
MYB-related_23 [comment=missing last 10 amino acids very divergent ] ET047612
ET046028
ET043712
MYB-related_26 [comment=full length] ET050114
ET044532
ET051600
MYB-related_27 [comment=3 prime half] ET042699
ET050567
ET049714
MYB-related_28 [comment=full length missing first 10 amino acids] ET044666
ET044562
ET050625
MYB-related_31 [comment=first 20 amino acids] ET045136
ET047973
ET049007
MYB-related_32 [comment=full length] ET044606
ET042359
ET042358
MYB-related_33 [comment=missing 5 prime 15 amino acids] ET044953
ET048555
ET044065
MYB-related_34 [comment=most of 3 prime end] ET043179
ET046757
ET043033
MYB-related_35 [comment=missing first 10 amino acids] ET044022
ET046459
ET045143
MYB-related_36 [comment=missing 5 prime 5 amino acids] ET047668
ET047666
ET047667
MYB-related_37 [comment=full length] ET045821
ET047798
ET041937
MYB-related_38 [comment=full length] ET044726
ET045004
ET049455
MYB-related_39 [comment=missing last 10 3 prime amino acids] ET045780
ET049984
ET047119
MYB-related_40 [comment=full length] ET050165
ET041965
ET046943
MYB-related_41 [comment=full length except first 9 amino acids] ET047240
ET048337
ET042163
ET044441
MYB-related_43 [comment=missing first 4 amino acids] ET049035
ET042424
ET048551
ET048574
MYB-related_45 [comment=full length] ET043615
ET049822
ET046814
ET044838
MYB-related_46 [comment=missing last 3 prime 15 amino acids] ET042902
ET042901
ET047416
ET049288
MYB-related_47 [comment=full length but missing first 10 amino acids] ET044202
ET044201
ET048814
ET045026
MYB-related_48 [comment=full but missing first 8 amino acids] ET042764
ET050755
ET044294
ET042765
MYB-related_49 [comment=full length and contains two MYB-related domains] ET043399
ET048795
ET044212
ET045208
MYB-related_51 [comment=full length] ET051509
ET051879
ET049001
ET046665
ET048094
MYB-related_52 [comment=full length] ET047212
ET047213
ET049713
ET043015
ET051095
MYB-related_54 [comment=full but missing last 8 amino acids] ET043823
ET044485
ET045824
ET046302
ET043960
MYB-related_56 [comment=full length] ET045928
ET045193
ET042493
ET049685
ET050611
MYB-related_57 [comment=full length but missing last 9 amino acids] ET042871
ET042870
ET042872
ET041883
ET042529
MYB-related_58 [comment=Full length] ET044545
ET051585
ET048828
ET043530
ET043664
MYB-related_61 [comment=first 20 amino acids divergent.] ET041800
ET049747
ET049547
ET043350
ET045934
MYB-related_63 [comment=full length] ET044948
ET044773
ET046951
ET043486
ET048284
ET047789
MYB-related_65 [comment=full length except last 8 amino acids] ET044831
ET049623
ET049594
ET050476
ET051052
ET044430
MYB-related_66 [comment=full length] ET043570
ET049364
ET049082
ET041680
ET048254
ET042784
MYB-related_67 [comment=3 prime half] ET041907
ET048788
ET043744
ET043461
ET051896
ET051898
ET051876
MYB-related_69 [comment=full length] ET050221
ET051761
ET048672
ET045657
ET045507
ET044452
ET049977
ET047415
MYB-related_70 [comment=full length] ET047499
ET050344
ET045103
ET048697
ET051390
ET049956
ET048354
ET047268
ET045911
MYB-related_71 [comment=full length except last 8 amino acids divergent.] ET050067
ET045232
ET043270
ET043227
ET043993
ET045376
ET043767
ET051393
ET047918
MYB-related_72 [comment=5 prime half] ET042482
MYB-related_73 [comment=full length] ET050817
MYB-related_74 [comment=full length] ET045482
MYB-related_75 [comment=appears full length] ET048919
MYB-related_76 [comment=first half but missing first 8 amino acids] ET044990
MYB-related_77 [comment=full length] ET051756
MYB-related_78 [comment=full length except first 6 amino acids missing] ET045127
MYB-related_79 [comment=3 prime half] ET045757
MYB-related_81 [comment=full length] ET045646
MYB-related_82 [comment=first half] ET043726
MYB-related_84 [comment=full length but very divergent] ET046038
MYB-related_85 [comment=appears to have 2 MYB-related domains and closest match has four domains.] ET044651
MYB-related_86 [comment=full length] ET046821
MYB-related_87 [comment=full length] ET043340
MYB-related_88 [comment=full length but missing first 10 amino acids] ET043874
MYB-related_89 [comment=full length divergent] ET045041
MYB-related_90 [comment=missing first 13 amino acids] ET048734


Tobacco published genes related to transcription factor family MYB-related
Family Genbank ID Name
Authors of this site:

Paul J Rushton
Marta T. Bokowiec
Xianfeng (Jeff) Chen
Thomas (Tom) W Laudeman
Jennifer F. Brannock
Michael P. Timko

Contact:

pr8y@virginia.edu